Contents

Introduction 1
C. W. Sensen

Application Domains
1 Genome Projects of Model Organisms 5
A. Pühler, D. Jording, J. Kalinowski
D. Buttgereit, R. Renkowitz-Pohl,
L. Altschmied, A. E. Danchin,
H. Feldmann, H.-P Klenk, M. Kröger
2 The Human Genome Project 41
L. C Tsai, S. 1F Scherer
3 GeneticDiscases 61
G. Dellaire
4 Pharmaceutical Bioinformatics and Drug
Discovery 105
C S. Ramanathan, D. B. Davison
5 Agri-Food and Genomics 127
1. A. P. Parkin, S. J. Robinson, A. G. Sharpe,
K. Rozwadowski, D. Hegedus, D. J. Lydiate
Bioinformatics

DNA Technologies
E. M. Zdabnov, R. Lopez, R. Apweiler,
6 Genomic Mapping and Positional Cloning.
with Emphasis on Plant Science 145
A. Vanarichit, S. Tragoonrung,
TToojinda
7 SequencingTechnology :165
L. R. Middendorf P G. Humphrey,
N. Narayanan, S. C. Roemer
8 A DNA Microarray Fabrication Strategy
for Research Laboratories 209
D. C. Tessier, E Benoit, T. Rigby, H. Hogues,
Van het Hoog, D. Thamas,
R. Braussenu

Potein Technologies
9 Two-Dimensional Gel Electrophoresis
and Mass Spectrometry for Proteomic
Studies: State-of-the-Art 223
D. Figeys
10 Proteome Analysis by Capillary Electro-
phoresis 253
N. J. Dovichi, Shen Hu, D. Michels,
Z. Zhang, S. N. Krylov
11 Using the Molecular Biology Data 263
T Etzold
12 Tools for DNA Technologies 285
P. Rice
13 ToolsforProteinTechnologies 309
D.S.Wishart
14 Structure Information 329
M. Cygler, A. Matte, J. D. Schrag
15 Genomic Data Representation through Ethical, Legal and Social Issues
Images - MAGPIE as an Example 345
P. Gordon, T. Gausterland, C. W. Sensen
16 InteractionDatabases 365
G. D. Bader, C. W. V. Hogue
17 Ethical Aspects of Genome Research and
Banking 381
B. M. Knoppers
18 Genomics - Five Years from Now 397
C. W. Sensen

Index 407
Color Figures see
http://www.wiley-vch.de/books/info/
3-527-30541-6