Part I Natural History and Genetic Diversity 1 Papaya (Carica papaya L.): Origin, Domestication, and Production . . 3 2 Biology of the Papaya Plant . . 17 3 Phenotypic and Genetic Diversity of Papaya . . 35 4 Vasconcellea for Papaya Improvement . . 47 5 The Phylogeny of the Caricaceae . . 81 Part II Classical and Molecular Genetics and Breeding 6 History and Future of the Solo Papaya . . 95 7 Hawaii's Transgenic Papaya Story 1978-2012: A Personal Account . . 115 8 Molecular Genetic Mapping of Papaya . . 143 9 Molecular Cytogenetics of Papaya . . 157 10 Physical Map of Papaya Genome . . 169 Part III The Papaya Genome 11 Sequencing and Assembly of the Transgenic Papaya Genome . . 187 12 Syntenic Sequence Conservation Between and Within Papaya Genes . . 205 13 Papaya Repeat Database . . 225 14 Genomics of Papaya Fruit Development and Ripening . . 241 15 Genomics of Papaya Disease Resistance . . 277 16 Genomics of Papaya Sex Chromosomes . . 309 Part IV Early Applications and Future Prospect 17 Physical Mapping of Papaya Sex Chromosomes . . 329 18 Cloning Major Genes Controlling Fruit Flesh Color in Papaya . . 341 19 Molecular Markers in Papayas . . 355 20 Papaya Nutritional Analysis . . 377 21 Papaya as a Medicinal Plant . . 391 22 Allele Discovery Platform (ADP) in Papaya (Carica papaya L.) . . 409 Index . . 423